Molecular Genetics of Bacteria

Book Description

Molecular Genetics of Bacteria fulfills the need for a comprehensive, primary textbook on bacterial and microbial genetics. Ideally suited for advanced undergraduate and graduate level courses, this book presents an interesting, modern perspective of the subject and offers descriptive background information, detailed experimental methods and data interpretation, examples of genetic analysis, and advanced material relevant to current applications of molecular genetics in biotechnology. The theme of genetic analysis is used to integrate all of the concepts presented in the text, with the pathogenesis and recombinant DNA techniques covered in their own chapters. Although the much-studied genetics of

E. coli are discussed throughout the book, many other microbial systems are introduced in order to show the breadth and diversity of the discipline of bacterial genetics. Chapters are pedagogically constructed and end with a review of key concepts, a set of discussion questions, a set of problems for exercise and testing assignments, and answers to the questions. An end of book glossary reviews all of the key terms found in the text. This book, extensively reviewed and class tested by instructors over the past four years, serves as an important text for all courses in bacterial and microbial genetics. TABLE OF CONTENTS: Introduction The Biological Universe What Is Genetics? Bacterial Genetics Phage Genetics A Brief History of Bacterial Molecular Genetics What's Ahead? Genes: Replication and Expression Introduction to Macromolecular Synthesis: Chromosome Structure and Replication Introduction to Macromolecular Synthesis: Gene Expression Genes and Genetic Elements Mutations in Bacteria Plasmids Conjugation Transformation Bacteriophages Transposition and Nonhomologous Recombination Genes in Action Molecular Basis of Recombination DNA Repair and Mutagenesis Regulation of Gene Expression Global Regulatory Mechanisms Genes in Practice Genetic Analysis in Phage Genetic Analysis in Bacteria Recombinant DNA Techniques and Cloning Bacterial Genes Molecular Genetic Analysis and Biotechnology

Customer Reviews:

Not a good choice for the visual learner.......2006-06-25

If you are a "visual learner," then this is NOT, I repeat, NOT, the book for you- I cannot emphasise this enough!

The text is very well written, however, the font used is rather small, and there are only FOUR colors used throughout the entire book.

The text is done entirely in light brown, black, grey and white.

Students like me -strongly visual learners- will be miserable; everyone else will like the book.

Fantastic introduction to the subject.......2005-08-01

This is one of few college textbooks I've used that has actually HELPED me learn the course material. The book takes you from the basics (DNA structure and replication, etc.) all the way through some very complex concepts while never missing a beat. It's surprisingly readable and student-user-friendly whether you're a beginner or a certifiable gene jockey. My only complaint is the quality of the figures; some of them are very small and thus hard to read, and as one reviewer commented, they are sort of simplistic to the point of not being very thorough. Having full-color illustrations would be a big plus.

Overall, this book definitely surpasses other bacterial genetics books I've seen as far as readability and organization goes. It delivers what it promises!

Very useful and informative.......2005-03-06

This book is great in developing the concepts and explaining in an easy but at the same time techinical way just what is involved in bacterial genetics. Teaching from the historical perspective you really get a sense of what these researchers were faced with and just how valuable their breakthoughs were. It doesn't try to be "hip" like so many other undergraduate textbooks out there, and for that they get full credit. The figures are a little simplistic though.

Excellent Book.......2004-03-26

This is an excellent and in-depth presentation of the molecular genetics of prokaryotes. Explanations are crystal clear throughout, and the diagrams are very well done. (Typographical errors are everywhere, but fortunately they are easy to spot and none of them are misleading.) The text can seem long at times, but the extra effort spent reading is repaid in terms of clarity. The authors are careful to insure everything is explained well. The book also covers several areas of prokaryotic biology besides molecular genetics, such as cell division, antibiotics, transport of molecules across the cell membrane, two-component signaling pathways, bacteriophages, and many others.

This is undoubtedly the best introduction to prokaryotic biology out there. Highly recommended.

A good book for microbial genetics.......2000-02-26

While many books in molecular biology explore about the eukaryotic cells, this book is designed for prokaryotic aspects. Most of the topics are about the E.coli the bacteria that we now know much about. However, some of the topics are somewhat complicated and misleading for an undergradaute student who still needs some backgrounds in bacterial genetics (A good example is where the authors draw the picture of the interaction between lac O1, O2 and O3 in the lac operon and that's wrong!)...The questions at the end of each chapters are nice and well prepared but a few of the answers given at the end of the book do not explain the point well enough. Overall, this is a good book for anyone who wants to know specifically in the field.

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If you like prokaryotes: go and get it!

Biology Of The Prokaryotes
Joseph W. Lengeler
Manufacturer: Blackwell Publishing
ProductGroup: Book
Binding: Hardcover

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ASIN: 0632053577

Customer Reviews:

If you like prokaryotes: go and get it!.......2000-07-27

The best microbiology book I've ever read (I haven't finished yet but it's still fun). I think it is the most up to date textbook in microbiology. It covers both biochemical and signal transduction pathways/networks in prokaryotes as well as principles in systematics and short introductions to medical microbiology and biotechnology. At the end of every chapter the various authors provide references to essential papers and reviews (instead to other books, like in Brocks Biology of Microorganisms) to start getting familiar with journals. The graphics are done with less colours but are very professional and as "easy" to understand as the topic they are representing (chemotaxis is not as easy as described in the stryer or brock). Maybe it's too much to read for undergraduates, but very useful for graduate students.

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Principles Of Bacterial Pathogenesis
Eduardo Groisman
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0123042208

Book Description

Principles of Bacterial Pathogenesis presents a molecular perspective on a select group of bacterial pathogens by having the leaders of the field present their perspective in a clear and authoritative manner. Each chapter contains a comprehensive review devoted to a single pathogen. Several chapters include work from authors outside the pathogenesis field, providing general perspectives on the evolution, regulation, and secretion of virulence and determinants.

Key Features
* Explains the basic principles of bacterial pathogenesis
* Covers diverse aspects integrating regulation, cellular microbiology and evolution of microbial disease of humans
* Discusses current strategies for the identification of virulence determinants and the methods used by microbes to deliver virulence factors
* Presents authoritative treatises of the major disease microorganisms

Average customer rating:

Good book for the proper reader.
A good book

Molecular Genetics of Bacteria
Jeremy W. Dale
Manufacturer: John Wiley & Sons
ProductGroup: Book
Binding: Paperback

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ASIN: 047085085X

Book Description

Expanded treatment of the development of bacterial structures, cellular communication, quorum sensing and two-component regulation.
Provides a distillation of key concepts of bacterial genetics to enhance student understanding.
Includes examples of the applications of genetics focusing on bacterial pathogenicity.

Download Description

The Fourth Edition of this highly successful book provides an essential introduction to the molecular genetics of bacteria. Thoroughly revised and updated, Molecular Genetics of Bacteria now includes a much greater coverage of genomics, microarrays and proteomics. An enhanced treatment of the ways in which both classical and modern genetics have contributed to our understanding of how bacteria work is included. The focus of the book remains firmly on bacteria and will be invaluable to those students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences. Expanded treatment of the development of bacterial structures, cellular communication, quorum sensing and two-component regulati Provides a distillation of key concepts of bacterial genetics to enhance student understanding. Includes examples of the applications of genetics focusing on bacterial pathogenicity.

Customer Reviews:

Good book for the proper reader........2002-05-29

I got a lot out of this book: not mastery of the subject, but the kind of feel for genetics you cannot get from a popular book on the subject. I occasionally had to skip material, but I rarely got frustrated. It is well written, and reasonably short. Its production values are somewhat lacking for the price: self references are to chapters, not chapter sections, and the diagrams are often amateurish, although sometimes very helpful. My background: very minimal organic chemistry (but the terms covalent bond and hydrogen bond weren't unknown to me), a popular science book on genetics under my belt, not very extensive knowledge of biology. A book such as "Dictionary of Modern Biology" by Norah Rudin is a definite help, and that book is very inexpensive.

A good book.......2000-09-19

This book has the minimun to know about molecular genetics of bacteria (I am studing this subject). The illustrations are clear and very good.I can very easily see this book being used to supplement lectures in an introductory course on biotecnology. I thoroughly recommend it.

Molecular Identification, Systematics, and Population Structure of Prokaryotes

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Molecular Identification, Systematics, and Population Structure of Prokaryotes
Erko, Ed. Stackerbrandt
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 3540231552

Book Description

Systematic biology has a far wider application than merely the provision of a reliable classification scheme for new strains. With the framework of the hierarchic system stabilizing, genomes, noncoding regions, and genes and their products can now be evaluated in an evolutionary context. This book summarizes recent developments in the molecular characterization of cultured and as-yet uncultured prokaryotes, emphasizing the strengths and weaknesses of individual approaches. The chapters of the book are compiled to stimulate students to enter the field of bacterial diversity, presenting a broad spectrum of fascinating multifaceted disciplines that illuminate the paths to ecosystem functioning, communication within communities, symbiosis, life in extreme environments, astrobiology, and more.

Biology Of Anaerobic Microorganisms (Environmental and Applied Microbiology Series)

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Biology Of Anaerobic Microorganisms (Environmental and Applied Microbiology Series)
ALEXANDER ED. ZEHNDER
Manufacturer: John Wiley & Sons
ProductGroup: Book
Binding: Hardcover

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ASIN: 0471882267

Microbial Phylogeny and Evolution: Concepts and Controversies

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Microbial Phylogeny and Evolution: Concepts and Controversies

Manufacturer: Oxford University Press, USA
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Binding: Hardcover

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Microbial Ecology: An Evolutionary Approach

ASIN: 0195168771

Book Description

The birth of bacterial genomics since the mid-1990s brought withit several conceptual modifications and wholly new controversies. Working beyond the scope of the neo-Darwinian evolutionary synthesis, a group of leading microbial evolutionists addresses the following and related issues, often with markedly varied viewpoints: DT Did the eukaryotic nucleus, cytoskeleton and cilia also orginate from symbiosis? DT Do the current scenarios about he origin of mitochondria and plastids require revision? DT What is the extent of lateral gene transfer (between "species") among bacteria? DT Does the rDNA phylogenetic tree still stand in the age of genomics? DT Is the course of the first 3 billion years of evolution even knowable?

Structural Biology of Bacterial Pathogensis

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Structural Biology of Bacterial Pathogensis
Gabriel, Ed. Waksman
Manufacturer: American Society of Microbiology
ProductGroup: Book
Binding: Hardcover

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ASIN: 1555813011

Bacterial Growth And Division: BIOCHEMISTRY AND REGUALTION OF PROKARYOTIC AND EUKARYOTIC CYCLES

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Bacterial Growth And Division: BIOCHEMISTRY AND REGUALTION OF PROKARYOTIC AND EUKARYOTIC CYCLES
STEPHEN COOPER
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0121879054

Book Description

How does a bacterial cell grow during the division cycle? This question is answered by the codeveloper of the Cooper-Helmstetter model of DNA replication. In a unique analysis of the bacterial division cycle, Cooper considers the major cell categories (cytoplasm, DNA, and cell surface) and presents a lucid description of bacterial growth during the division cycle.
The concepts of bacterial physiology from Ole Maaløe's Copenhagen school are presented throughout the book and are applied to such topics as the origin of variability, the pattern of DNA segregation, and the principles underlying growth transitions.
The results of research on E. coli are used to explain the division cycles of Caulobacter, Bacilli, Streptococci, and eukaryotes. Insightful reanalysis highlights significant similarities between these cells and E.coli.
With over 25 years of experience in the study of the bacterial division cycle, Cooper has synthesized his ideas and research into an exciting presentation. He manages to write a comprehensive volume that will be of great interest to microbiologists, cell physiologists, cell and molecular biologists, researchers in cell-cycle studies, and mathematicians and engineering scientists interested in modeling cell growth.

Key Features
* Written by one of the codiscoverers of the Cooper-Helmstetter model
* Applies the results of research on E. coli to other groups, including Caulobacter, Bacilli, Streptococci, and eukaryotes; the Caulobacter reanalysis highlights significant similarities with the E. coli system
* Presents a unified description of the bacterial division cycle with relevance to eukaryotic systems
* Addresses the concepts of the Copenhagen School in a new and original way

Bacterial Pathogenesis: A Molecular Approach

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A Thorough and Sophisticated Presentation of Pathogenicity

Bacterial Pathogenesis: A Molecular Approach
Abigail A. Salyers , and Dixie D. Whitt
Manufacturer: ASM Press
ProductGroup: Book
Binding: Paperback

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ASIN: 1555810705

Customer Reviews:

A Thorough and Sophisticated Presentation of Pathogenicity.......2000-04-23

As an undergraduate student studying microbiology, I found the book to be extremely technical. I would have appreciated a more clinical approach to pathogenicity. Bacterial Pathogenesis can, however, serve as an excellent reference text concerning the details of pathogenicity on a molecular level. The book covers virulence factors and antibiotic in detail. 21 bacterial diseases are covered extensively, each having its own chapter.

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