Novel Methods In Molecular And Cellular Biochemistry Of Muscle (DEVELOPMENTS IN MOLECULAR AND CELLULAR BIOCHEMISTRY)

Book Description

Experimental techniques are the life blood of science. The better the methodology is, the more reliable and accurate the results will be. Ultimately, this will lead to a clearer interpretation of those results and firmer conclusions from any set of experiments. Experimental methodology in the area of cardiovascular biochemistry and molecular biology has advanced considerably in the last decade. Because of these factors, it was thought that a focused issue of Molecular and Cellular Biochemistry dedicated to the novel, latest technological advances in the field was warranted. We must thank Dr Naranjan S. Dhalla, Editor-in-Chief of Molecular and Cellular Biochemistry, for his willingness to publish an issue with such a focus. We have attracted some of the leaders in the field of cardiovascular biology to submit articles describing some of the most novel, significant techniques currently in use in their laboratories. The purpose of the manuscripts was not to describe the recent experimental findings from each laboratory as is done in most conventional manuscripts. Instead, the purpose of the articles found within this focused volume of Molecular and Cellular Biochemistry was to describe how the technique is performed on the laboratory bench so that others less familiar with the technique may be able to use it in their own labs. The subjects described in this volume can be generally subdivided into three categories: molecular biology, cell biology and basic biochemistry. The methods cover wide areas including various DNA and RNA expression technologies, transfection techniques, quantification of ion flux movement, measurements of lipid metabolism, advances in the culture of specific cardiovascular cell populations, and the use of confocal microscopy to examine cell structure and function. We thank all of the authors who have contributed so much of their time and efforts and, most importantly, shared the `secrets' of these valuable techniques with the rest of the cardiovascular research community.

Customer Reviews:

The Best Travel Journal.......2007-04-15

I purchased this journal for my first trip abroad ten years ago, and have purchased one for each of my trips since. It's size makes it easy to carry in a day bag or carry-on luggage. Space is provided for phone numbers, addresses and e-mail addresses. Credit card numbers, packing list, expense lists, etc are all included. This journal is a must for all travelers!

Great Travel Journal.......2007-03-31

Have used this product before. It has all the space and categories I like in a travel journal.

A must have travel journal.......2005-09-24

This is my second journal like this and it is wonderful. It is the perfect size for my purse and easy to write in while traveling. I especially love the cover that protects it from dirt and stains. It has a place inside the cover front and back to keep extra receipts and postcards in while traveling. It is a must for anyone who wants to keep a record of their travel adventures.

Travel Journal of Choice.......2003-05-10

I have used the "Everywoman's Travel Journal"
for seven European trips, and have found it
exceptionally useful. As other reviewers have
mentioned, it contains pages to record
traveling expenses, film notes, an address
section, maps, calendar (missing in newer
editions), and space to record your complete
itinerary.

One thing I especially like is the fact that
the spine doesn't crack, and the pages do not
fall out, even with rough handling. There is
a clear plastic dustjacket, with space to store
postcards, tickets, and the like. The journal
is compact, and fits easily into a purse or
pocket. There are plenty of pages to record
extensive daily notes.

Of all of the Travel Journals I have seen or bought,
this one is my favorite.

A journaling traveler.......2002-06-17

I came upon this journal several years ago and have purchased one to complete with every subsequent trip. I now possess a mini-library of my travels. The journal contains outstanding tips on packing, foreign customs relating to women, and time/temperature conversion. Address book, travelers checque and film logs, and a designated space for copies of passport/ID/travel documents make this a complete, handy package that makes this a travel-must for me. The only downside is that, not having been updated recently, some of the reference data is out-dated. I also miss the calendars that were a handy part of the first edition. Despite this, it's still a fantastic way to document your travels.

Book Description

A lively, detailed picture of village life in the Middle Ages by the authors of Life in a Medieval City and Life in a Medieval Castle. "A good general introduction to the history of this period."--Los Angeles Times

Customer Reviews:

Solid introduction.......2003-10-30

Life in a Medieval Village by Frances and Joseph Gies. Recommended.

Life in a Medieval Village is one of a series, including Life in a Medieval City and Life in a Medieval Castle, written by Frances and Joseph Gies. This series rarely touches upon the great people and events romanticized by Hollywood and numerous fiction writers (and perhaps even a few historians), but focuses on the basics of everyday life for the average person or even the average lord or cleric. The Gies use a number of primary and secondary sources, the latter of which reveal how the historian's view of the medieval village has changed in the 20th and 21st centuries and how flexible historians must be in interpreting the evidence.

Researched and written for the layperson, Life in a Medieval Village is more accurately about life in an English medieval village, with most of the detail coming from the records of Aethelintone/Aethelington/Adelintune/Aylington (Elton) in Huntingdon, one of Ramsey Abbey's manors. The Gies provide a history of the village concept and its definition; its role in the manorial system (contrasted to the seigneurial system); a description of its people, physical structure, buildings, administration and administrators, judicial system, family and spiritual life, and work; and the background behind its decline.

The world of Elton and similar villages is not found in movies or novels. Social and economic statuses are not always clear cut, economic upward mobility is possible primarily through acquisition of land, and even the distinction between "free" and "unfree" is not distinct. Life revolves around the manor and the villeins' and cotters' obligations to the mostly absent lord and the manor, which come in the form of work, rents, fees, taxes, and fines. The administrative structure of the manor is somewhat like that of a modern corporation, with the lord as CEO of multiple manors (and primary consumer of goods) who "wanted the certainty of rents and dues from his tenants, the efficient operation of his demesne, and good prices for wool and grain." His steward, or seneschal, serves as senior executive, while the bailiff, reeve, beadle, woodward, and others are the manor's day-to-day managers and supervisors.

As the villagers acquire surnames (from where they live, what they do, the offices they hold, and personal characteristics), patterns emerge from the records. Some families become dominant economically and politically (e.g., holding many offices such as reeve or juror many times); others decline; while yet others show a propensity for violence and petty crimes. Such infractions are punished primarily with fines rather than corporal punishment; the stocks and hanging are resorted to only in the most egregious cases. The judicial system is often compassionate (or at least practical); many fines for minor trespasses are lowered or forgiven by the court because "she is poor." When laws are broken, a jury hears the case, but the entire village decides.

The Gies also provide an excellent overview of the passing of the medieval village, which began with a sustained famine and the Black Death. The labor-intensive manorial system simply could not survive the depletion of workers, the increase in expenses, the onerous taxes brought on by wars, and, perhaps more importantly, the sense of change and discontent that began to pervade the villein class.

The challenge for the Gies as authors is to take the minimal material available (ranging from books about estate management written for lords and stewards to court and ecclesiastical records) and to bring the village to life from these records. What emerges are people who live in fragile houses; are rarely well fed from a nutritional perspective and whose food supply is always in doubt; work hard and are not above trying to wheedle out of work; who drink and fight and are sometimes brutal; fornicate (primarily a woman's crime but not a particularly reviled one); vandalize; commit petty crimes against the lord and their neighbors; and in short live lives of struggle every day without the expectation or vision of change in the future.

The Gies focus on Elton, with supplemental material from other English villages, so the reader who is interested in village life on the continent will need to explore other works to flesh out the picture. Because the mostly illiterate villagers themselves left few personal records, it is up to the thoughtful reader to discern the village's character and personality and to conceive of what day-to-day life must have been, based on the little that is known-to put oneself into the worn shoes of the working villein and to imagine his or her thoughts, feelings, and aspirations. Life in a Medieval Village is a good beginning.

Diane L. Schirf, 30 October 2003.

Lifeless.......2003-06-20

On the positive side, this book contains an enormous quantity of well-documented detail and scholarship. On the negative side, the writing is colorless and, to my eye, devoid of any unifying theme. Even someone seriously interested in the history of the period will find it soporific. Having struggled to the end, I still cannot decide if the juice was worth the squeeze.

Well sourced, but doesn't read well........2003-05-16

Renowned scholars of medieval history, the Gies credentials are impeccable. However, in this book, they seem to relish in providing piece after piece of redundant references, notes, and other bits of trivia to tirelessly pound the reader into submission as they seem determined to impress with their knowledge and research capabilities. If nothing else, the work provides the reader with a comprehensive bilbliography and reference list of places to go if they are that interested in life in a medieval village. The result of this style is a dry work that ofter reads like paragraph after paragraph of a census roll or register. It's dry, it's well researched, but it's dry. Oh, did I say that already?

A bit dry but very informative.......2003-05-03

Gies&Gies discuss the nature of an "open field" village, which was a distinctive feature of the "manorial" or feudalism (more or less). It was not just a small town; the nature of the agricultural and legal systems made it unique.

Lots of material, and well worth reading, but occassionally dry and pedantic.

Good enough for what it does.......2003-04-20

I can see from the other reviews to date that I'm not the only reader that found Life in a Medieval Village a bit dry. Some of the records Gies and Gies dug up are detailed here, but the narrative can turn into paragraphs long description of how John was fined sixpence for letting his sheep graze in the church, and so forth. I'm also not surprised to see that other readers found little depth or analysis. The authors walk the line between scholarly research and popular history, and I'm not sure many people will be satisfied with this.

If you are seriously interested in the subject, and you want details, this would be the book to choose. But I don't think it would be good in isolation. It's really not a fun read, and specialist historians probably wouldn't get much out of it.

I did read one other reviewer who liked it for a very good reason, and that is if you are considering fictional writing, perhaps historical fiction or the fantasy genre. I've also seen the Gies books listed in various Amazon.com lists for running role playing game campaigns. Having played RPGs myself in high school, I can say that all the Gies books (of the two I've read, this one and the Castle book, with Cities coming in a few weeks from now probably) would indeed be a valuable reference, because the reader will find the sort of day to day detail that is well suited to that work. It also contains a lengthy list of references and a short glossary of terms, so as a common reference and mildly enjoyable read, Life in a Medieval Village is an alright book.

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Life in a Medieval Castle and Village Coloring Book by John Green

Nice coloring book

Inexpensive, interesting way to learn about the Middle Ages

THESE COLORING BOOKS ARE EXCELLENT!

Life in a Medieval Castle and Village Coloring Book

Life in a Medieval Castle and Village Coloring Book
John Green
Manufacturer: Dover Publications
ProductGroup: Book
Binding: Paperback

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ASIN: 0486265420

Book Description

A panorama of life in the Middle Ages in 42 realistically detailed drawings ranging from scenes of everyday life in castle, village, monastery, and countryside, to dramatic and colorful portrayals of tournaments, castle sieges, banquets, the building of a cathedral, battles, fairs, and more. Introduction. Detailed captions.

Customer Reviews:

Life in a Medieval Castle and Village Coloring Book by John Green.......2006-06-25

LOVE IT!!!!! Great pics, great content, just plain great!!!

Nice coloring book.......2005-10-22

I like the idea of this coloring book, but was a little dissapointed because I would have enjoyed more pictures of ladies. There was probably only three woman in the whole coloring book. It was mostly scenes from life around the castle, of people in different aspects of castle work. Very interesting and lovely pictures otherwise.

Inexpensive, interesting way to learn about the Middle Ages.......2003-08-06

This coloring book is well-drawn and contains very interesting information about living as a serf, peasant, tradesman, or noble person during the Middles Ages. My children are 7 and 9 years old, and they are enjoying coloring the pages and adding them to their history notebook. I am learning quite a bit myself! Great value.

THESE COLORING BOOKS ARE EXCELLENT!.......2002-06-11

The Dover Coloring books are all excellent! They are also an awesome value! We own and use over 20 of these coloring books for history and science. They are extremely detailed and educational, but even my 6 year old loves to color them! This book covers from the fall of the Roman Empire to the rise of the merchant class and features pictures like daily activities of those in the castle, warfare, jousting, archery, hunting, gardens, courtship, Ladies, nobility, feasts, serfs and peasants, skilled workers, crime & punishment, fairs, religion, technological advances, etc. HIGHLY RECOMMENDED!!

Life in a Medieval Castle and Village Coloring Book.......2000-12-17

Life in a Medieval Castle and Village Coloring Book by John Green is an excellent resource for anyone, children or adult, looking for a brief overview of life in the Middle Ages. The line drawings and text give clear views of many elements of medieval society from serf to noble; skills needed for defense and hunting to those of economic development-weaving, milling, blacksmithing, lumbering, marketing-are revealed with interesting detail and accuracy.

Top quality educational entertainment for home or school in a fascinating book of coloring fun portraying a dramatic and exciting period of history. Teacher recommended.

Average customer rating:

Medieval stereotypes

A unique and memorable read

Women Should Read This Book and Be Happy!

We need not scrutinize to enjoy

Medieval life makes me feel lucky about post-industrial life

Down the Common: A Year in the Life of a Medieval Woman
Ann Baer
Manufacturer: M. Evans and Company, Inc.
ProductGroup: Book
Binding: Paperback

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ASIN: 0871318741

Book Description

Ann Baer has produced a sensitive, knowledgeable month-by-month account of the hardships suffered by Marion and Peter Carpenter, set from March through the following February of one year of their struggle for existence in Medieval England.... Ann Baer has given the world an immeasurable gift with the writing of Down the Common. Her attention to detail paints a crystal clear picture of the pain, the beauty of nature, and the steadfastness of people to whom each day was unceasing toil. --The Midwest Book Review.

Customer Reviews:

Medieval stereotypes.......2007-10-10

This book is a good try at writing sympathetically about ordinary medieval people at some era or other (it's not at all clear which). It's an easy book to love because you run into a wide variety of people and situations, some happy, some not. Reading it leaves you feeling that you know something of what life was like for ordinary people in the countryside during a historical period when most of the history focuses on kings, knights and battles.

Unfortunately the book suffers from a couple of major flaws. One is that it seems to be based on research that is somewhat dated. The author also paints a simple and very generalized picture, and her vagueness about the exact time and place leads to the impression that what she depicts is "typical" for (as others have said) a wide range of times and places. A few examples:

Marion, for instance, *never* washes herself and hardly ever her clothing, even when her child (forgive me for being gross here) has thrown up all over her. Medieval people may not have immersed themselves in bathtubs on a regular basis, but that doesn't mean they couldn't or didn't keep clean; a basin and washrag work perfectly well and were used by many right up through the early 20th century.

Marion also doesn't sweep her floor, and (if I recall correctly) her dirt floor is shown as muddy and dusty. In reality, dirt floors were most often "finished" with some sort of clay mixture and binder (ox blood is one example) and well beaten down, producing a floor that may not have been completely hard and durable, but was certainly as hard as adobe, and much more practical than loose dirt. And we know from archaeological finds that people did sweep floors and throw trash outside the house rather than just letting it build up.

Another example: Linen in the book is seen as a rare and exotic cloth; everyone wears wool, even for underclothes, and a gift of linen to the village squire's wife is the occasion for much admiration. In reality, flax for linen was grown in Britain continuously, at least from Roman times, and while it took a lot more processing than wool to produce a finished cloth, it was also much more durable and easier to wash, making it especially suitable for the under-layers of clothing.

The absence of newspapers (and low levels of literacy) also certainly did not mean people had *no* way of finding out what was going on in the world outside their homes or no curiosity about it. As others have said, there was widespread foot traffic between villages and to regional markets, a constant local trade in cows, sheep, cheese, and many other things, and there were pilgrims, traveling preachers, and itinerant craftsmen in all ages (not to mention beggars, who could at least be a source of news).

The "nasty, brutish and short" view of medieval life was widely thought to be the "reality" as recently as the 1950s, and in fact you will still see such a picture of the Middle Ages presented in the movies. But newer research reveals quite a different and more complex picture. While there was certainly dirt, poverty, sickness and misery in many places, the ideas of cleanliness, neatness, thrift, improvement and skill were certainly known and were diligently cultivated and practiced by many.

I have to admit I didn't like Marion, the main character, much: she is depicted as a "dreamer," and as the only one with an eye to see and appreciate natural beauty. Even by comparison with others in her own village, however, she struck me more as someone who was lazy, distractable, and lacking in initiative or persistence: someone who didn't live up to her own potential. I also don't think the appreciation of a sunny morning, dew on the grass or fresh water were foreign ideas to a bunch of dull peasants -- to which Marion was the only exception! There is plenty of medieval literature to counteract that notion.

The second problem I saw in this book was that it seemed to me to have been written with a checklist in hand. There are a lot of different vignettes and situations described. The problem is, many characters seem to exist *only* to provide an example of some medieval situation, and have no relationship to the rest of the plot (such as it is). There is one ignorant priest: check. One adventurous person who visits (gasp!) the village in the next valley: check. One worker who dies from an infected wound that would have been trivial with modern antibiotics: check. One extremely slovenly family that neglects their children. A few children who die young. One slightly wealthier family in the manor house. And so forth.

The one I really noticed was that when the squire's lady's second child dies soon after birth, the scene practically has giant-sized letters all over it spelling RH-FACTOR INCOMPATIBILITY. I am skeptical in general of the book's impression that people didn't recognize particular health problems when they saw them. They could not have known the real causes in many cases, but they certainly would have had their own theories, and attempts at remedies, some of which would have done *some* good (though admittedly not in this case).

I admit I'm being rather hard on this book, but it annoys me when a novel that is supposed to give "insight into the Middle Ages" gives instead an impression that is over-simplified, outdated and unnecessarily depressing. It may comfortably reinforce our feeling of superiority over those Poor Medieval Peasants, but it doesn't really give us a lot of insight into people who were so like us in some ways, even under circumstances and in a culture we find very difficult to imagine.

A unique and memorable read.......2007-05-07

I first read this book in 1997, it is still one of my favorites, and I have never come across anything quite like it again. I read for pleasure a great deal and enjoy fiction with some historical fact, that has a believable character I can relate to, and isn't just written in the same usual formula. For me, this book has stood the test of time.

Women Should Read This Book and Be Happy!.......2007-01-16

I bought this copy for my best friend because American women should read this book and realize how wonderful modernity is for mothers. Everyone I have recommended this book to has really enjoyed it. It is a well written window into the life of a medieval woman and her daily trevails and hardships. Fascinating.

We need not scrutinize to enjoy.......2006-12-17

I am a student of Medieval history, and I understand that some people feel the need to make everything historical authentic to within an inch of its life. But, I believe that this is one of those novels that is excellent, despite a few anachronisms. Just shut off the part of your brain that says, "That's not what such-and-such wrote in his annals about rural life," and enjoy a good story with a very strong Medieval feel.

Every time has had people who live a day-to-day mundane life without respite. Try reading women's letters from the Victorian era if you think Marion's life is boring.
Not everyone had fairs, markets, pilgrims, and visitors. Even today, you are lucky if you find someone in my home town with cable TV. There will always be communities that are isolated, or even just a bit more out of touch than others.

Just stop over-analyzing and read the book.

Medieval life makes me feel lucky about post-industrial life.......2005-09-12

Recommended by a friend, this was my first historical novel. Generally, I read non-fiction. I found reading Down the Common a wonderful experience - very much worth my time. While I wondered at times what was researched historical fact and what was a description from the mind of the writer, reading the book was engrossing, entertaining and enlightening. It was over too quickly.

The life Marion, the protagonist, was dreary and full of disappointment, hardship, danger and drugery. All in the village were illiterate so they know no history further back than the oldest villager can remember. They very rarely traveled away from the village overnight. Getting enough food was a serious problem; obtaining medicine even worse. The odds of surviving childhood were daunting, and people could die from an infection following an injury from a splinter.

These people had nothing, yet they shared everything. In spite of immense hardships, they loved and laughed and took care of each other. It makes me feel like my own problems are very small, so while reading the book evokes sadness much of the time, I'm left with a feeling of gratefulness of the condition of my own life in the post-industrial society. My problems are trivial and fleeting compared to Marion, and her family and neighbors.

I thoroughly enjoyed reading Down the Common, and eagerly await another novel from Ann Baer. I understand she was 82 years old when she published her first book.

Village Life in Ancient Egypt: Laundry Lists and Love Songs

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Village Life in Ancient Egypt: Laundry Lists and Love Songs
A. G. McDowell
Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback

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ASIN: 0199247536

Book Description

Deir el-Medina, the village of the workmen who built the royal tombs in the Valley of the Kings, is a uniquely rich source of information about life in Egypt between 1539 and 1075 BC. The abundant archaeological remains are complemented by tens of thousands of texts documenting the thoughts and activities of the villagers. Many of the texts are written on papyrus but most are on flakes of limestone which, being free and readily available, were used for even the most casual and temporary of records. They include private letters, administrative accounts, magic spells, records of purchases, last wills and testaments, laundry lists, and love songs. The value of these rare glimpses of daily life is greatly enhanced by the concentration of texts in one time and place. This book combines translations of over 200 of these texts spanning the entire range of preserved genres with stunning illustrations. The reader will, therefore, be able to experience the life of the villagers through their own words whilst viewing places known to each individual writer. Each text is introduced by a commentary that provides the context and explains the contribution each text makes to our understanding of Egyptian society at this period.

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Life In A Medieval Village
Morgan
Manufacturer: Lerner Publications Company
ProductGroup: Book
Binding: Hardcover
ASIN: 0082251207

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Life in a Medieval Village
Frances Gies; Joseph Gies
Manufacturer: Harper Perennial
ProductGroup: Book
Binding: Paperback
ASIN: B000QYBDQU

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Life in a Medieval Village
Frances Gies
Manufacturer: HARPER & ROW
ProductGroup: Book
Binding: Paperback
ASIN: B000WTQMA6

Life in a Medieval Village (A Cambridge Topic Book)

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Life in a Medieval Village (A Cambridge Topic Book)
Gwyneth Morgan
Manufacturer: Lerner Pub Group (L)
ProductGroup: Book
Binding: Library Binding

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ASIN: 0822512076

Book Description

A portrayal of the everyday life of a peasant family, the parish church, and the manor within a typical village in 13th century England.

Medieval Realms - Town and Country Life (Medieval Realms)

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Medieval Realms - Town and Country Life (Medieval Realms)
Peter Chrisp
Manufacturer: Lucent Books
ProductGroup: Book
Binding: Hardcover

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ASIN: 1590185366

Book Description

Though there were distinct classes of people during the Middle Ages-nobility, clergy, peasants, and the various levels between the three-daily life activities and cultural rituals often unified the populace. All people participated in pilgrimages, warfare, markets and fairs; none among them escaped the Plague.

Medieval Town And Country Life (History Topics)

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Medieval Town And Country Life (History Topics)
Emma Johnson
Manufacturer: Sea to Sea Publications
ProductGroup: Book
Binding: Hardcover

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Yves Behar Fuseproject: Design Series 2 (Sfmoma Design Series, 2)
Joseph Rosa , and Yves Behar
Manufacturer: Gingko Press
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Binding: Paperback

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