Book Description
A new edition of a bestseller, this book covers the changes that occur with normal aging and disease processes from a physiological basis. Filled with illustrations and tables, it covers topics such as gGenetics of aging, developments in Alzheimer's, new treatments for Osteoporosis, new medications for Diabetes, new treatments for Gastritis, and new Nsaids to treat Degenerative Joint Diseases.
Customer Reviews:
Lab Guide.......2005-10-03
The lab guide is very helpful for the lab. It was very specific and detailed.
An excellent manual for teaching decriptive embryology.......2001-05-02
I witnessed the birth of the first edition of this book when I was still a college student, and have seen its transformation to suit the needs of each new era. The book offers fundamental principles in descriptive embryology. I hoped to see more on the expperimental aspect of the subject. I also wished to see the embryology of more of the animal phyla (eg. fruit fly, zebra fish) included.
An Embryology Lab Instructor's Comments.......2000-04-28
I have used this book in my course for four years. Typically one-hundred students per year are enrolled in my course. The quality of the photomicrographs is excellent. My only criticisms of the micrographs are that 1.) The sequence of the photomicrographs would be enhanced if they were arranged in a developmental sequence. Presently, the student must flip pages constantly to view all slides relevant to a particular developmental stage. 2.) There are not enough sagittal sections of the chick embryos. 3.) 96 hour chick embryos, instead of pig embryos might be an improvement. The text is good, although not quite as thorough as the Matthews lab manual was.
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Mouse Development: Patterning, Morphogenesis, and Organogenesis
Janet, Ed. Rossant
Manufacturer: Academic Press
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Manipulating the Mouse Embryo: A Laboratory Manual
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Atlas of Mouse Development
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Anatomical Basis Of Mouse Development
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Mouse Phenotypes: A Handbook of Mutation Analysis
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The Laboratory Mouse: Handbook of Experimental Animals (HANDBOOK OF EXPERIMENTAL ANIMALS)
ASIN: 0125979517 |
Book Description
This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference.
*Broad-based overview of mouse development from fundamental to specialist levels
*Extensive coverage of a wide range of developmental mutations of the mouse
*Excellent benchmark illustrations of brain, craniofacial, gut and heart development
*In-depth experiment-based assessment of concepts in mammalian development
*Focus on models of specific relevance to human development
*Comprehensive reference to key literature and electronic databases related to mouse development
*High-quality full-color production
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Molecular Basis Of Epithelial Appendage Morphogenesis (Molecular Biology Intelligence Unit)
Cheng-Ming Chuong
Manufacturer: LANDES, R.G. COMPANY
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ASIN: 1570594902 |
Book Description
Epithelial appendages are the derivatives of the epithelial sheet. On the body surface, they include hair, feathers, scales, claws, horns, sebaceous glands, mammary glands, etc. In the oral cavity, they include teeth, salivary glands, etc. Inside the body, the surfaces of the gut are covered with different derivatives that line the stomach, small intestine, colon, etc. Lung, pancreas and liver begin as epithelial derivatives of the endodermal tube. These organs are diverse in structure and function. However, is there a common theme underlying their formation?This book identifies simple principles underlying the seemingly diverse phenomena of organ formation. Data accumulated so far suggest that most of the molecular mechanisms are shared in different organogenetic processes, in body axis construction, and even have their roots in Drosophila morphogenesis. The new unifying concept is a pleasure to appreciate. Each chapter provides the most up-to date information written by leaders in the field.
Book Description
Molecular Cancer Therapeutics covers state-of-the-art strategies to identify and develop cancer drug target molecules and lead inhibitors for clinical testing. It provides a thorough treatment of drug target discovery, validation, and development. The introductory chapters provide an overview of pathways to discovery and development of molecular cancer therapeutics. Subsequent chapters progress from initial stages of drug target discovery to drug discovery, development, and testing in preclinical and clinical models. Topics include drug lead screening, drug-to-lead development, proof-of-concept studies, medicinal chemistry issues, intellectual property concerns, and clinical development.
This invaluable reference promotes understanding of steps involved in developing drug leads for industrial partnering and development. It provides an overview of the strategies for discovery and validation of drug target molecules, and discusses cell- and molecule-based drug screening strategies, as well as mouse models for cancer. Coverage also includes how to refine drug leads for suitability in clinical testing, the special issues of clinical testing of molecular-targeted drugs, and intellectual property concerns.
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Anticancer Drug Development
Bruce C., Ed. Baguley
Manufacturer: Academic Press
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Binding: Hardcover
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ASIN: 0120726513 |
Book Description
Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided.
KEY FEATURES:
* One work that can be consulted for all aspects of anticancer drug development
* Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts
* A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death
* Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products
* Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques
* Hundreds of references that allow the reader to access relevant scientific and medical literature
* Clear illustrations, some in color, that provide both understanding of the field and material for teaching
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The Igf System: Molecular Biology, Physiology, and Clinical Applications (Contemporary Endocrinology)
Ron G., Ed. Rosenfeld
Manufacturer: Humana Press
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ASIN: 0896036928 |
Book Description
Influential researchers comprehensively survey the basic and clinical aspects of the insulin-like growth factor system. Their state-of-the-art synthesis of a broad range of IGF research illuminates the interplay among ligands, receptors, and binding proteins, each exerting both the local and systemic effects that constitute this complex system. The book examines in detail not only the molecular biology, the biological actions, and the physiology of the various IGF systems, but also the clinical aspects of the IGF system, ultimately producing a useful paradigm for the investigation of related hormone, growth factor, and cytokine signaling systems. The IGF System: Molecular Biology, Physiology, and Clinical Applications is the first extended treatment of the IGF system in many years and is designed to serve as the new standard reference-of-choice for all basic and clinical investigators, as well as practicing physicians treating a range of human diseases, including cancer, diabetes, and neurodegenerative disorders.
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Morphology, Molecules, Evolution and Phylogeny in Polychaeta and Related Taxa (DEVELOPMENTS IN HYDROBIOLOGY)
Bartolomaeus T.
Manufacturer: Springer
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Binding: Hardcover
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ASIN: 1402029519 |
Book Description
Annelida, mainly consisting of marine Polychaeta and in faunal and partly parasitic Clitellata, is one the most significant metazoan taxa. Its more than 20.000 described species invade nearly all habitats and play a central role in marine benthic systems as well as in terrestrial soil communities. Annelids include all soft-bodied segmented worm-like organisms and have been recognized as a separate "phylum" for almost 200 years.
Recently, evidence has been accumulated which shows that some of the groups formerly regarded as independent "phyla" such as Pogonophora (now recognized as Siboglinidae), Echiura, Myzostomida and perhaps Sipuncula, are most probably nothing else than greatly modified Annelida. The extreme morphological diversity found especially in Polychaeta displays the plasticity of a simple segmented organisation that basically is nothing else but a serial repetition of identical units. Thus, annelids are highly important to our understanding of fundamental questions about morphological and adaptive diversity, as well as clarifying evolutionary changes and phylogenetic relationships.
The book aims to summarize our knowledge on Polychaetes polychaetes and their allies and gives an overview of recent advances gained by studies that employed conventional and modern methods plus, increasingly and importantly, the use of molecular markers and computer-assisted kinship analyses. It also reflects the state of art in polychaete sciences and presents new questions and controversies. As such it will significantly influence the direction of research on Polychaeta and their related taxa.
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Molecular Breeding of Forage and Turf (Developments in Plant Breeding)
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover
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ASIN: 1402018673 |
Book Description
Forage and turf are the backbone of sustainable agriculture and contribute extensively to the world economy. The fast-paced advancement of cellular and molecular biology provides novel methods to accelerate or complement conventional breeding efforts. This book contains the most comprehensive reviews on the latest development in applications of molecular techniques for the improvement of forage grasses, forage legumes and turf grasses. Detailed accounts and future opportunities in molecular breeding of forage and turf, from gene discovery to development of improved cultivars, are described in the book. Almost all relevant areas are explored in detail, including tolerance to biotic and abiotic stresses; flowering control; plant-symbiont relations; breeding for animal, human and environmental welfare; molecular markers; transgenics; bioinformatics; population genetics; genomics of the model legume
M. truncatula; field testing and risk assessment as well as intellectual property rights. This book will be of interest to researchers in both academia and industry who are involved in forage and turf improvement. It will be especially important to breeders, molecular biologists, geneticists, physiologists and agronomists.
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Nucleic Acid Research: Future Development
Manufacturer: Academic Pr
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Binding: Hardcover
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ASIN: 0125016506 |
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- Pieces of My Heart: Writings Inspired by Animals and Nature
- Principles of Neural Science
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- Subantarctic Campbell Island
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