BRS Physiology (Board Review Series)
Average customer rating: 5 out of 5 stars
  • Great for USMLE.
  • Physiology
  • Best Physiology Review Book
  • The gold standard for physiology on Step 1
  • Good review
BRS Physiology (Board Review Series)
Linda S Costanzo
Manufacturer: Lippincott Williams & Wilkins
ProductGroup: Book
Binding: Paperback

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ASIN: 0781773113

Book Description

Thoroughly updated for its Fourth Edition, BRS Physiology is an excellent aid for students preparing for the USMLE Step 1. The book concisely reviews key physiological principles and includes clinical correlations throughout to emphasize connections between basic physiology and clinical medicine. Numerous illustrations, tables, and flow charts help students visualize material quickly and aid in long-term retention. End-of-chapter USMLE-style questions and a comprehensive end-of-book exam test the student's problem-solving skills, and clearly explained answers guide the student through the correct steps in reasoning. This edition features increased coverage of pathophysiology, new questions, and a new two-color design and artwork.

Customer Reviews:

5 out of 5 stars Great for USMLE........2007-09-27

Consistently good book, easy to read, useful information in logical order. Pretty much all you have to know on Physio for Step 1.

5 out of 5 stars Physiology.......2007-09-14

This book is fabulous!!! It's one of the best physiology books I've read. I highly encourage purchasing it. Plus, it's a great FNP board review book with great questions at the end of the chapters!

5 out of 5 stars Best Physiology Review Book.......2007-08-11

Hands down the best resource for physiology. Respiratory and Acid-Base chapters were a bit weak, but overall, the book was excellent.

5 out of 5 stars The gold standard for physiology on Step 1.......2007-07-27

Great to use during 1st and 2nd year in supplement to your medschool classes. My boards will be this summer, but this book is widely regarded as the gold standard for physiology preparation for the USMLE/COMLEX step 1..This book is also a condensed version of the bigger physiology boook by costanzo (same author) so if you dont understand anything in the BRS, you should refer to the bigger Costanzo book. I highly recommend at least the BRS for boards.

5 out of 5 stars Good review.......2007-07-12

Good review of physiology. Used it for my shelf exam and USMLE Step 1 and it covered most of the important things
Asking About Cells
Average customer rating: 5 out of 5 stars
  • Book helps engineers looking at an introduction to Biology
  • blood is not a bad sight to see
Asking About Cells
Allan J. Tobin , and Richard E. Morel
Manufacturer: Brooks Cole
ProductGroup: Book
Binding: Hardcover

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ASIN: 0030980186

Book Description

The main goal of ASKING ABOUT CELLS is to evoke from students a desire to learn more about cell biology, which stems from gaining an understanding of the processes by which researchers discover the connections between cells and the rest of biology. By breaking down the typically encyclopedic walls of molecular and cellular detail, this text concentrates on presenting material through the energy of inquiry, revealing to students the questioning nature of cell biology. This exciting new cell biology text is designed for a one-semester, introductory course for instructors who wish to emphasize basic concepts and principles. This text portrays and emphasizes how the ongoing process of scientific inquiry has led to our knowledge of how cells operate. In this new text, cell biology is portrayed as a dynamic blend of curiosity and observation that has led to new questions and to a continuing quest to understand fundamental life processes.

Customer Reviews:

5 out of 5 stars Book helps engineers looking at an introduction to Biology.......2002-11-28

I was an engineer and interested in learning about Biology. I went to a bookstore and browsed for 4 hours looking for a book that I could comprehend. Only two books fitted the bill - the first one is "Asking about Cells" by a Harvard Professor and the second one is "An Introduction to Genetic Analysis" by Griffith, published by whfreeman. I purchased both the books and I find that they are both good. It helps to read the "Asking about Cells" to put more detailed cellular functions in Griffith's book in perspective. Also, check out the "DNA from the Beginning" tutorial published free online by Cold Spring Harbor Labs. It also gives a glimpse of what is in store.

The main purpose of the book is to remove any phobia one might have towards biology. It neatly explains that Biologists do not know everything about cells (a common misconception of non-biologists). It also shows how they know as much as they know today. Finally, it has passionate interviews from the researchers who say why they continue to do biology daily.

The material is basic enough to be followed, at the same time, informative enough to go to the next level - understanding how genes work. I myself have now become a researcher in biology, thanks to this book. If you have never done biology ever in your life, this book is for you.

5 out of 5 stars blood is not a bad sight to see.......1999-05-09

before blood hits your skin it is blue then it turns to re
Biomaterials Science And Biocompatibility
Average customer rating: 1 out of 5 stars
  • A wasted opportunity...
Biomaterials Science And Biocompatibility
Frederick Silver
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 0387987118

Book Description

This text for students and researchers, takes an interdisciplinary approach to describing the chemistry and physics of materials, their biocompatibility, and the consequences of implantation of devices made of these materials into the human body. The reader is introduced to the principles of polymer science and the study of metals, ceramics and composites, and also to the basic biology required to understand the nature of the host-transplant interface. Topics covered in this book include the macromolecular components of cells and tissues, self-assembly processes, biological cascade systems, microscopic structure of cells and tissues, immunology, transplantation biology, and the pathobiology of wound healing. Topics covered in the materials science chapters include the structures and properties of polymers, metals, ceramics and composites, and the processes for forming materials as well as the pathobiology of devices. The final two chapters deal with tissue engineering and the relations between the biology of cells and tissue transplantation, and the engineering of tissue replacements using passaged cells.

Customer Reviews:

1 out of 5 stars A wasted opportunity..........2000-03-23

Very little biomaterials science involved at all. Previous text by Silver was a far better primer for biomaterials science. A disapointment.
Ion Channels of Excitable Membranes (3rd Edition)
Average customer rating: 5 out of 5 stars
  • Excellent and useful text.
  • Destined to become an Oprah Book Club selection
  • Keeps getting better with each Edition
  • Rara avis
  • A classic. Still authoritative.
Ion Channels of Excitable Membranes (3rd Edition)
Bertil Hille
Manufacturer: Sinauer Associates
ProductGroup: Book
Binding: Hardcover

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ASIN: 0878933212

Book Description

Ion channels underlie a broad range of the most basic biological processes, from excitation and signaling to secretion and absorption. Like enzymes, they are diverse and ubiquitous macromolecular catalysts with high substrate specificity and subject to strong regulation. This fully revised and expanded Third Edition of Ion Channels of Excitable Membranes describes the known channels and their physiological functions, then develops the conceptual background needed to understand their architecture and molecular mechanisms of operation. It includes new chapters on calcium signaling, structural biology, and molecular biology and genomics. Ion Channels of Excitable Membranes begins with the classical biophysical work of Hodgkin and Huxley, continues with the roles of channels in cellular signaling, then develops the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ion Channels of Excitable Membranes is written to be accessible and interesting to life scientists and physical scientists of all kinds. It introduces all the concepts that a graduate student should be aware of but is also effective in advanced undergraduate courses. It has long been the recognized authoritative overview of this field used by all neuroscientists.

Customer Reviews:

5 out of 5 stars Excellent and useful text........2006-11-17

This text is an encyclopedia of information from kinetics to structure to interactions. It's got a reserved space on my academic bookshelf.

5 out of 5 stars Destined to become an Oprah Book Club selection.......2005-12-08

Some books have opening sentences that grab you in an instant. "Call me Ishmael." "It was the best of times, it was the worst of times." And now, Hille joins the list of authors to reach out and grab us, with the awe-inspiring "Ion channels are macromolecular pores in cell membranes."

Even after my fifth reading, that line still gives me the shivers.

But it takes more than a brilliant opening to make a great book, and Hille delivers. From a distinctly jaunty derivation of the Nernst equation to the page-turning thrills of non-stationary fluctuation analysis, the book is hard to put down. It does bog down a little in Chapter 10, "Elementary Properties of Ions in Solution"--after all, is there anyone who isn't already aware of the fundamentals of electrodiffusion? But this is really a minor trifle in an otherwise masterful work.

It's just a matter of time before Oprah gives this book a nod; buy it now and avoid the rush!

5 out of 5 stars Keeps getting better with each Edition.......2002-03-27

This book is a must-have for anyone working with excitable cells, be they experimentalists or modelers. It's a great reference book; everything is clearly indexed and almost compulsively cited. I've been using this book since its first edition, and it just keeps getting better each time.

5 out of 5 stars Rara avis.......2002-02-09

This classic deserves all the praise it gets. It is an excellent introduction to the molecular biology of channels, told with an eye to history as well as science.

5 out of 5 stars A classic. Still authoritative........2001-08-13

This is an authoritative textbook on ion channels that is often quoted in numerous textbooks in neurophysiology. Hille himself has contributed a lot in this field. The Hogkin-Huxley model is the de facto standard model in neurophysiology but certain things about neurons cannot be explained only with voltage-controlled sodium and potassium channels. With the patch-clamp technique, we have found a way to explore other interesting channles. To remind you, there are a world of ion channels! Hille's textbook show there are indeed a variety of channels most of which are poorly understood. As a reviewer below has commented, it also gives a unique insight into the history of neural membrane research. Concepts are explained with clearity. Details measurement techniques.
I of the Vortex: From Neurons to Self
Average customer rating: 4.5 out of 5 stars
  • Thinking as an internalized movement!
  • Readable and wide-ranging, but all from just one theoretical perspective
  • Amazing Neuroscience synthesis!
  • read it.
  • Very worthwhile
I of the Vortex: From Neurons to Self
Rodolfo R. Llinas
Manufacturer: M.I.T. PRESS
ProductGroup: Book
Binding: Hardcover

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ASIN: 0262122332

Amazon.com

What is it about neuroscience that graces its practitioners with humility? Rodolfo Llinas of the NYU School of Medicine continues this tradition of quietly tackling the deepest issues in I of the Vortex. This exposition on the evolution and development of consciousness is accessible and intriguing enough to interest readers more philosophically than scientifically oriented. Grounded in research, the book posits our awareness as an artifact of the cortico-thalamic binding of perceptions and movements in synchrony; Llinas uses this theory as a launching pad for more far-reaching considerations of selfhood all the more relevant for their correlation with the facts.

Charmingly illustrated with artistic and scientific images cleverly supporting the arguments, the book is a quick if challenging read, and it explains all the scientific basics for those approaching from the humanities. Synthesizing evolution, philosophy, and neuroscience is becoming an increasingly popular endeavor for introspective eggheads, and we should be grateful: the question of consciousness affects us all and touches on every other field, from theology to particle physics. I of the Vortex is a welcome contribution to the theory of mind and essential reading for the introspective. --Rob Lightner

Book Description

In I of the Vortex, Rodolfo Llinas, a founding father of modern brain science, presents an original view of the evolution and nature of mind. According to Llinas, the "mindness state" evolved to allow predictive interactions between mobile creatures and their environment. He illustrates the early evolution of mind through a primitive animal called the "sea squirt." The mobile larval form has a brainlike ganglion that receives sensory information about the surrounding environment. As an adult, the sea squirt attaches itself to a stationary object and then digests most of its own brain. This suggests that the nervous system evolved to allow active movement in animals. To move through the environment safely, a creature must anticipate the outcome of each movement on the basis of incoming sensory data. Thus the capacity to predict is most likely the ultimate brain function. One could even say that Self is the centralization of prediction.

At the heart of Llinas's theory is the concept of oscillation. Many neurons possess electrical activity, manifested as oscillating variations in the minute voltages across the cell membrane. On the crests of these oscillations occur larger electrical events that are the basis for neuron-to-neuron communication. Like cicadas chirping in unison, a group of neurons oscillating in phase can resonate with a distant group of neurons. This simultaneity of neuronal activity is the neurobiological root of cognition. Although the internal state that we call the mind is guided by the senses, it is also generated by the oscillations within the brain. Thus, in a certain sense, one could say that reality is not all "out there," but is a kind of virtual reality.

Customer Reviews:

5 out of 5 stars Thinking as an internalized movement!.......2007-06-24

Jorge Borges wrote, "I am not sure that I exist, actually. I am all the writers that I have read, all the people that I have met, all the women that I have loved; all the cities that I have visited, all my ancestors... Perhaps I would have liked to be my father, who wrote but has the decency of not publishing".
In the book "I of the vortex" Rodolfo Llinas gives another perspective on who am "I" and where "I" comes from, looking into the deep and dark recesses of the brain as a neuroscientist and physician, leaving God out from the game, unlike his maestro John Eccles, a dedicated theist, who wrote that "there is a Divine Providence operating over and above the materialistic happenings of biological evolution".
The ultimate thesis Llinas nominates is: "thinking is an internalized movement". He makes his point very clearly, based on his extensive knowledge and experience both as a scientist and writer. Perhaps thinking is an internalized movement? Perhaps not! The book "I of the vortex" is the ultimate read for those who ask Questions. An excellent book.

4 out of 5 stars Readable and wide-ranging, but all from just one theoretical perspective.......2006-10-23

What is the "self" in neural terms? Few would be bold enough to claim an answer to that question. Yet in "I of the Vortex: From Neurons to Self," Rodolfo Llinas sketches a very compelling picture of how the self, consciousness, and intelligence may arise in the brain.

Essentially, Llinas's argument goes as follows. First, brains are really only found in animals that move (so, obviously, plants do not have brains). In fact, at least one animal - the sea squirt - actually devours its own brain once it no longer needs to move. Although simple movements might be caused by oscillatory pattern generators in the spinal cord, the brain is necessary for more complex, sensory-guided movement. Why should this be so?

The answer Llinas provides is prediction, or in other words, a sensorimotor internal model of the world based on "dt lookahead" functions, interfacing the motor and sensory systems. Synchronized oscillations from the cerebellum (Llinas's area of expertise) carry out the motor-side of this computation, giving rise to the characteristic 8-12 Hz periodicity of the neural signals that command voluntary movements. At a higher frequency (40 Hz), other neuronal oscillations throughout the thalamocortical system serve to bind sensory representations together. And the subjective, cognitive correlate of the intersection of these oscillations is no less than the self: "this temporally coherent event that binds, in the time domain, the fractured components of external and internal reality into a single construct is what we call the 'self.'"

But wait, doesn't that mean that all animals have a sense of "self"- even the lowly sea squirt (at least before it eats its brain)? It would seem so. But that's not the end of Llinas's more controversial claims. Llinas also suggests that neural networks explain "very little concerning the actual functioning of the nervous system itself," advocating instead the idea that most of our cognitive abilities are genetically prewired at birth. Along these lines, Llinas endorses Chomsky's idea that genes may to a large extent determine language, and furthermore that language exists in many species besides homo sapiens.

It is here that "I of the Vortex" starts to seem more like a manifesto than a careful scientific analysis. For example, after introducing the basics of neurophysiology and comparative neurology in the first half of the book, Llinas skips the cognitive level of analysis almost altogether and starts extrapolating directly to issues of consciousness, awareness, and selfhood. This bias against direct investigations of cognition (something arguably very important for understanding consciousness) is nowhere more apparent than when he refers to cognitive neuroscience as "neophrenology." But without this important middle-level of analysis, Llinas is mostly shooting from the hip in the second half of the book - and aiming for concepts that are simply too far removed from Llinas's expertise in cellular neurophysiology.

On the whole, Llinas has done an admirable job of outlining one particular view of how neuronal dynamics may give rise to consciousness in an embodied cognition framework. In this sense, "I of the Vortex" makes an excellent companion to other high-level introductions to cognitive neuroscience.

5 out of 5 stars Amazing Neuroscience synthesis!.......2005-08-14

The book presents an amazing Neuroscience synthesis that covers all the aspects: from ions to synergistic systems. It gives a thought-provoking explanation of the origin of the brain through evolution. It also explains the concepts of 'qualias' and 'fixed action patterns' in such an integrative manner and concludes that everything was perfectly made to synergistically create our predictive brains.

5 out of 5 stars read it........2004-09-07

If you are going to read one book about neuroscience, consciousness, or the meaning of life, this should be it. Dr. Llinas has made some unusually innovative and profound assertions about how the self ("soul") might be generated from the mechanical workings of the brain. While the answer to the hard problem of consciousness remains elusive, I can honestly say after having read many books on the subject, that this is as close as it gets.

5 out of 5 stars Very worthwhile.......2002-05-20

The author presents quite a plausible theory of mind, based on his work as a neuroscientist. I suspect Llinas is very much on the right track to illuminating the physical basis of consciousness.

Building chapter-by-chapter simultaneously on the apparent evolutionary development from the simplest neuronal system to the centralized brain, and on the results of brain scans and other experiments, Llinas brings us calmly and reasonably to the resultant human mind of today.

For Llinas, consciousness is the synchronized 40Hz firing of regions of the cortex over time. That is, consciousness is not just a given pattern of firing in 3-space, but is a 4-space relation. That additional dimension of time multiplies enormously the potential number of brain patterns that could occur in an individual. But it also makes the topic that much harder to study.

The writing feels like it has been written by someone who knows alot: there are many points where conceptual connections are not made entirely explicit (because it probably seemed so self-evident to Llinas) and the reader must fill in those gaps. Also, some of his non-neurologic language is quite technical: the description of the "self" as a calculated eigenvector, or the "vortex" which is essentially an attractor (as known in mathematics), that can make Llinas sound like a cold, hard-nosed scientist.

However, Llinas is refreshingly 'human'. For him, it is quite reasonable to assume (as a common consequence of evolution and similarity of brain structure) that many other species have forms of consciousness. Indeed, he devotes an entire chapter to qualia, and contends that qualia exist as essential brain feature, not only for humans but for cats and dogs and most other animals with brains of the same evolutionary genre (and that even in the case of invertebrate (octopus) brains he argues that the burden of proof is on those who would deny qualia).

One caveat: be aware that Llinas does not explicitly delineate between accepted facts and his theory - the book flows as one whole. It is not intented as deception. As he says in the preface "This book presents a personal view of neuroscience...".
From Neuron to Brain: A Cellular and Molecular Approach to the Function of the Nervous System, Fourth Edition
Average customer rating: 5 out of 5 stars
  • Condition of new book from Amazon is not new.
  • Excellent Book for Neuroscience
  • A great introductory book on neuroscience
  • Clear, concise, helpful text for a beginning grad student!
  • Neurophysiology (History & Evolution)
From Neuron to Brain: A Cellular and Molecular Approach to the Function of the Nervous System, Fourth Edition
John G. Nicholls
Manufacturer: Sinauer Associates
ProductGroup: Book
Binding: Hardcover

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ASIN: 0878934391

Book Description

In the 25 years since From Neuron to Brain was first published, the authors' aim has remained constant—to describe how nerve cells go about their business of transmitting signals, how the signals are put together, and how, out of this integration, higher functions emerge. The new Fourth Edition, while maintaining this focus, has been completely reformatted and updated.

The emphasis, as before, is on experiments, and on the way they are carried out. Using a narrative approach, the authors follow a line from the original inception of a new idea to an account of research being done today. The wealth of new facts, techniques, and concepts, however, presented a challenge in keeping the book to a manageable size. Inevitably, the authors have had to delete descriptions of certain classical experiments.

Largely in response to readers' comments, elements of format and presentation have been changed for this new edition—more headings have been introduced, the paragraphs are shorter, and the illustrations, now in full color, have been clarified. As in previous editions, references are cited throughout the text, and appendices are provided to help readers unfamiliar with the nervous system deal with essential facts and definitions.

Intended for use in upper-level undergraduate, graduate, psychology, and medical school Neuroscience courses, From Neuron to Brain will be of interest to anyone, with or without a specialized background in biological sciences, who is curious about the workings of the nervous system. It presents a readable and coherent account of how cellular and molecular approaches can provide insights into the workings of the brain.

Customer Reviews:

3 out of 5 stars Condition of new book from Amazon is not new........2007-09-11

I realize that Amazon uses different shippers and stuff but I would not recommend buying this book from Amazon b/c, first of all, it took 6 days for it to ship to me when I have 2 day shipping and because I paid for a new one(direct from Amazon) and the copy I was shipped already had scratches and water damage on the inside pages although it was wrapped in clear plastic and supposedly new. This is not the first time where things like this have happened but I think this will be the last time. I am canceling my 2 day shipping and have decided to use other sources for my textbook and other book needs after my vouchers are used up.

5 out of 5 stars Excellent Book for Neuroscience.......2006-04-01

Neuroscience is generally considered a very dry area of research where people do research for years together to discover some meager facts. Still, even to a person who is averse to Neuroscience, this book might seem appealing. This speaks about the lucid, simple way of explanation in this book. This book is well written and explains the basics of Neuroscience better than any other giant books in market. Buy this book irrespective of your discipline to know the intricacies of Human Brain and have a pleasant reading.

5 out of 5 stars A great introductory book on neuroscience.......2005-08-12

I am a physics graduate student who happen to become interested in neuroscience. I had been searching for an introductory book when I stumbled upon this one. Although I am only half-way through the book right now, I could already tell that it is exactly what a newcomer to this field would need. With the terminology clearly defined, the book gives a very concise, clear, and logic description on the fundamentals. It further keeps one's interest high by relating the fundamental knowledges to everyday experiences. What I like most about this book is that it does not shy away from pointing out what is not yet known. With the last chapter devoted to "open questions", it presents the real questions to be answered. This book is really perfect. Highly recommended.

5 out of 5 stars Clear, concise, helpful text for a beginning grad student!.......2004-10-19

I am a first year graduate student "accidentally" entering the field of neuroscience. I needed a basic text to help me "catch up". This book has been wonderful! The authors' have a great writing style- easy to read. More importantly, the authors are expert at choosing and presenting important, basic aspects of neurobiology to inexperienced neuroscientists without bogging the reader down with unnecessary and confusing detail. In particular, the authors thoroughly discuss ion channels and their role in neuronal communication, presenting electrophysiology as a valuable tool for studying these channels. This text was "just right" for me. However, if you are an advanced "neuroscientist", this text might be a bit on the "simple" side.

5 out of 5 stars Neurophysiology (History & Evolution).......2004-06-11

This book is similar in format and style to Principles of Neural Science by Kandel, Schwartz, & Jessell. Nicholls book is half the length of Kandel's, yet just as good. Colored drawings & diagrams are laced throughout the text. It is strongest in auditory physiology, synaptic transmission, vision physiology, & neural development. Clear graphs and line-drawings of intracellular and extracellular recordings abound. Give this book its chance. It should be on the reading list for Medical & Graduate School.
Molecular Biology Of The Female Reproductive System
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    Molecular Biology Of The Female Reproductive System
    J., ED. FINDLAY
    Manufacturer: Academic Press
    ProductGroup: Book
    Binding: Hardcover

    GeneralGeneral | Animals | Biological Sciences | Science | Subjects | Books
    Cell BiologyCell Biology | Biology | Biological Sciences | Science | Subjects | Books
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    Generative OrgansGenerative Organs | Reproductive & Sexual | Medicine | Subjects | Books
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    ReproductionReproduction | Reproductive & Sexual | Medicine | Subjects | Books
    Obstetrics & GynecologyObstetrics & Gynecology | Specialties | Medicine | Subjects | Books
    Endocrinology & MetabolismEndocrinology & Metabolism | Internal Medicine | Medicine | Subjects | Books
    Endocrinology & MetabolismEndocrinology & Metabolism | Internal Medicine | Medicine | Medical | Professional & Technical | Subjects | Books
    ReproductiveReproductive | Internal Medicine | Medicine | Medical | Professional & Technical | Subjects | Books
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    ASIN: 0122563654

    Book Description

    New techniques in cellular and molecular biology have increased our understanding of the mechanisms controlling reproductive function in the female. Emphasizing these new techniques, Molecular Biology of the Female Reproductive System provides a state-of-the-art review of local regulatory mechanisms that control reproductive processes. Stressing the interface of endocrinology, immunology, and cell biology, this book concentrates on the autocrine, paracrine, and endocrine systems that regulate both the functions of the ovary and uterus and the interaction between the early embryo and the mother.

    Key Features
    * Covers the mechanisms controlling reproductive function in the female
    * Offers a cellular and molecular approach to the control of reproductive function
    * Focuses on the ovary and uterus, and includes a discussion of the early embryo, including
    * Hormonal control of folliculogenesis and luteal function
    * Cell-cell interactions in the follicle
    * Role of cytokines in regulating steroid and protein hormone production
    * Endocrine receptors and mechanisms in ovulation
    * Cell biology of the oviduct and uterus
    * Migratory cells
    * Paracrine regulation
    * Hormones of the trophectoderm and early placenta
    * Interaction between trophectoderm and endometrium
    * Provides extensive references
    Power, Sex, Suicide: Mitochondria and the Meaning of Life
    Average customer rating: 5 out of 5 stars
    • everything a popular science book should be
    • Ohh mitochondria, tell us the truth
    • Simply the most fascinating book I have read in years
    • The ATP Powerhouses
    • It *is* a life-changing book!!!
    Power, Sex, Suicide: Mitochondria and the Meaning of Life
    Nick Lane
    Manufacturer: Oxford University Press, USA
    ProductGroup: Book
    Binding: Paperback

    Cell BiologyCell Biology | Biology | Biological Sciences | Science | Subjects | Books
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    Similar Items:
    1. Oxygen: The Molecule that Made the World (Popular Science) Oxygen: The Molecule that Made the World (Popular Science)
    2. Genesis: The Scientific Quest for Life's Origins Genesis: The Scientific Quest for Life's Origins
    3. Life on a Young Planet: The First Three Billion Years of Evolution on Earth (Princeton Science Library) Life on a Young Planet: The First Three Billion Years of Evolution on Earth (Princeton Science Library)
    4. The Making of the Fittest: DNA and the Ultimate Forensic Record of Evolution The Making of the Fittest: DNA and the Ultimate Forensic Record of Evolution
    5. Endless Forms Most Beautiful: The New Science Of Evo Devo And The Making Of The Animal Kingdom Endless Forms Most Beautiful: The New Science Of Evo Devo And The Making Of The Animal Kingdom

    ASIN: 0199205647

    Book Description

    Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford

    Customer Reviews:

    5 out of 5 stars everything a popular science book should be.......2007-09-30

    While this book is not easy reading, I cannot recommend it highly enough.
    Nick Lane does not try to oversimplify the intricacies of the molecular biology
    underlying the workings of a cell, but shows how the details are necessary to
    understand how and why it all came to be. I am amazed at how he managed
    to distil a vast quantity of mostly very recent scientific research into not only
    a readable, but also a visionary book. The speculative parts of the book need
    to be taken with a grain of salt. However, after reading this book my attention
    is drawn to articles on mitochondria in Nature and Science, articles which I would
    certainly have shirked before reading this book.

    5 out of 5 stars Ohh mitochondria, tell us the truth.......2007-09-17

    What a book, absolutely fascinating and highly recommended, although I must say that this is not an easy book, in fact is kind of complex if you are not acquainted with the subject. This is not a critic, thing is I would not change a bit of it, but in my opinion, people should have a little knowledge of cellular metabolism and biochemistry before attempting this book.

    After reading Dawkins book about the selfish gene, it was inevitable for me to wonder about life origins, why unicellular organisms have that tendency to complexity and to group itself, and how all this machinery works. This book provide a thorough and absorbing introduction of Mitochondria and its symbiosis with eukaryotes, what is the function of each one, why there are two sexes and why we aged and finally become history. As you will see, our understanding of these matters is rather modest, the author insinuate possible solutions to some of the big questions, but in any case the subject is so interesting that you read this book excited all the way to the end.

    How beautiful is life and how complex ... you can see that just watching a little fly and wonder how on earth this insect manage to fly, as if eukaryotes have a previous knowledge of Physics, as if they have all the basic solutions of nature in a template. I just know one thing: I want to know and read more about it.

    5 out of 5 stars Simply the most fascinating book I have read in years.......2007-07-19

    I cannot over recommend this book. It ranks alongside "The Selfish Gene" by Richard Dawkins as one of the seminal books for understanding life on earth. Interestingly, the title doesn't oversell the book at all - it really does contain fascinating information about power, sex and suicide (albeit cell suicide). If you have any interest in evolution or the origins of life - just get this book.

    5 out of 5 stars The ATP Powerhouses.......2007-07-16

    The power of "mighty"chondria enthralled me to my very cells. Science, power, intrique...like a great mystery novel that takes place within the cell...

    Note: reading this book in public elicits stares. The title jumps out, but not the subtitle.

    5 out of 5 stars It *is* a life-changing book!!!.......2007-05-14

    Well, all right... Enthusiasm might trump my common sense a little, here. Not everyone will change their outlook on life after reading this highly interesting and eye-opening book, but it certainly convinced me of the central role that mitochondria likely played in the evolution of eukaryotic cells and of multicellular organisms. I had to change my opinion on the relative importance of getting a nucleus or getting mitochondria during our evolutionary journey; mitochondria, which up to now I had unfairly considered as rather boring ATP factories and mere actors in the process of apoptosis, now do indeed seem to be the architects of life as we know it.

    Nick Lane does a great job at integrating the relevant scientific literature and weaving it into an all-audience book filled with exciting facts and clever hypotheses. Among popular science writers, he is certainly among the best; the same appears to be true as a theory-builder.

    This is a must-read book for all biologists, and a "really, really should be read" book for anyone else.
    Cytokines in Health and Disease: Second Edition, Revised and Expanded (Cytokines in Health and Disease)
    Average customer rating: Not rated
      Cytokines in Health and Disease: Second Edition, Revised and Expanded (Cytokines in Health and Disease)

      Manufacturer: Informa Healthcare
      ProductGroup: Book
      Binding: Hardcover

      BiochemistryBiochemistry | Biological Sciences | Science | Subjects | Books
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      ImmunologyImmunology | Basic Science | Medicine | Subjects | Books
      MicrobiologyMicrobiology | Basic Science | Medicine | Subjects | Books
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      Communicable DiseasesCommunicable Diseases | Infectious Disease | Internal Medicine | Medicine | Medical | Professional & Technical | Subjects | Books
      ASIN: 0824798236

      Book Description

      Reflecting the exponential growth in the field of cytokine research, this extensively rewritten and expanded Second Edition presents new findings on cytokines, their clinical uses, and potential future therapeutic developments-consolidating the latest experimental and clinical studies into a highly readable single-source volume.

      Nutrient Modulation Of The Immune Response
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        Nutrient Modulation Of The Immune Response
        SUSANNA, ED. CUNNINGHAM-RUNDLES
        Manufacturer: Marcel Dekker
        ProductGroup: Book
        Binding: Hardcover

        GeneralGeneral | Nutrition | Health, Mind & Body | Subjects | Books
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        NutritionNutrition | Basic Sciences | Medical | Professional & Technical | Subjects | Books
        ASIN: 0824784480

        Book Description

        This book demonstrates that nutrients play a direct role as co-factors and regulators of the immune system. The book also shows that modulating the immune response with nutrients can provide a fundamental approach to preventive medicine.;Containing nearly 2300 bibliographic citations as well as illustrative figures, tables, and micrographs, this book is designed to be of interest to clinical immunologists, immunology and vitamin researchers, nutrition specialists, paediatricians, neonatologists, and upper-level undergraduate, graduate, and medical school students in these disciplines.

        Books:

        1. Buffalo Before Breakfast (Magic Tree House 18, paper)
        2. Cabin Fever: Dialogues with Nature
        3. California Coastal Access Guide
        4. California the Beautiful
        5. Carl Linnaeus: Father of Classification (Great Minds of Science)
        6. Children and Nature: Psychological, Sociocultural, and Evolutionary Investigations
        7. Coastal Fish Identification: California to Alaska
        8. Complete Novels: Red Harvest / The Dain Curse / The Maltese Falcon / The Glass Key / The Thin Man (Library of America)
        9. Confessions of a Barbarian: Selections from the Journals of Edward Abbey, 1951-1989
        10. Coral Reef Coloring Book

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